The Entourage Effect~We Need More THC!
4th Dec 2024
MAY 17, 2018 First discovered in 1988, by EB Russo, the Entourage Effect describes the benefits of full spectrum medicine and the results that can be achieved versus medicine comprised of a single molecule.
What does this mean?
A single molecule, an isolated compound that has been removed from its original state existing within a complex structure combined with other compounds that complement it's properties in a synergistic way.
The number of cannabinoids found in the Hemp/Cannabis plant are growing all of the time due to research, we know there at least 80 different cannabinoids present. CBD and THC are only 2 of them, in the research that has been done, these two cannabinoids have been been found to treat over 250 known medical conditions. Yes, you heard that right!
In this research, they discovered the incredible benefits of the two combined versus separate. There are also over 500 different compounds found in the plant, over 200 different terpenes. Terpenes are the aroma you smell from any plant when you get a whiff of the flower's own characteristic terpene profile.
These various molecules each have their own properties accompanying feelings, moods, etc. that are specific to that plant's constitution. Just within the Terpene family alone, and how they work together is a subject for another blog. Within the Hemp/Cannabis plant, each Terpene affects disease in it's own way and certain Terpenes target specific diseases more effectively than others.
In his research, Dr. Russo found that the results of full spectrum medicine caused 2-4x greater effects than THC alone. Another study found full spectrum medicine produced effects 330% higher.
CBD mitigates the effects of THC, in combination the results have been incredible, alone the studies have shown each cannabinoid to have amazing results, for some who have tried one or the other and have claimed to not have seen any results, such as someone who has tried smoking pot before and someone who has tried CBD Oil before. Neither one of them have equal parts.
Because CBD mitigates the psychoactive effects of THC, most recreational growers have been breeding varieties with little or no CBD, so that the psychoactive components are not interfered with. Most CBD Oils on the market only contain .3% THC, as this is the legal amount allowed. Even this tiny amount while not having any psychoactive component, can still stimulate the Entourage Effect.
In my experience, more people achieve the desired results with even just one of the cannabinoids than with any other medicine available to mankind at this time. But for that small percent of people who claim to not have seen the results they desire from CBD, maybe they need a little more THC in their CBD Oil than the legal limit allows, in that case, you could get your medical marijuana card and you would have access to many different ratios of CBD and THC combinations and you could use your instincts to adjust your dose to the desired effects.
For example, if you needed 200mg of CBD oil to achieve the desired results for anxiety, you might reach it sooner with a ratio of 2mg of CBD and 2mg of THC, because they complement each other and all of the components found in the plant help to deliver the plant's properties to the specific cells that they need to be delivered to as well as assisting in the proper release and absorption of the compounds, etc. Accordingly, if a patient experimented with THC alone, perhaps they need to up the CBD, various strains have different ratios and these can be smoked, vaped, ingested in oil or edibles.
So much more are present as well, including vitamins A, C and E, naturally occurring B Complex, minerals like zinc, potassium, calcium, phosphorous, iron, magnesium, contains all 20 amino acids. So if for some reason, you have not achieved the desired results with the Cannabis plant, perhaps, it was because all of the plant's beneficial components were not present or maybe you just didn't have your ratios down. Because we all have an Endocannabinoid System, there is really no reason why it shouldn't work for you, too. Be patient, figure out the dose right for you and feel the healing begin...